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Condition

Insulin Resistance

Quick answer

Insulin resistance is a metabolic condition where the body's cells respond less effectively to insulin, raising blood sugar over time. It is the precursor to type 2 diabetes. GLP-1 medications like semaglutide improve insulin sensitivity, support weight loss, and reduce diabetes risk when combined with diet and exercise.

About Insulin Resistance

When cells stop responding well to insulin, your pancreas compensates by producing more — a state called hyperinsulinemia. Over years this drives weight gain, energy crashes, and eventually type 2 diabetes. GLP-1 therapy directly improves insulin sensitivity while supporting weight loss.

Common signs & symptoms

  • Energy crashes after meals
  • Stubborn abdominal weight
  • Sugar cravings
  • Skin tags or dark patches (acanthosis nigricans)
  • Elevated fasting insulin or HOMA-IR

Risk factors

  • Family history of type 2 diabetes
  • PCOS
  • Sedentary lifestyle
  • Excess refined carbohydrate intake
  • Visceral adiposity

Treatments at ZenOryva

Common questions

Will losing weight reverse insulin resistance?

Often yes. Significant weight loss — particularly visceral fat reduction — improves insulin sensitivity dramatically. GLP-1 medications accelerate that process.

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