Compounded Semaglutide
The most studied GLP-1 medication, prescribed by independently licensed providers and prepared by licensed compounding pharmacies.
Quick answer
Compounded semaglutide is a GLP-1 receptor agonist with the same active ingredient as Ozempic and Wegovy, prepared by licensed compounding pharmacies under prescription. ZenOryva members start at 0.25 mg weekly, titrate over 4 to 8 weeks, and typically lose 15 to 20 percent of body weight when paired with lifestyle support.
- Active ingredient
- Semaglutide
- Class
- GLP-1 receptor agonist
- Administration
- Subcutaneous injection
What it is
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics a naturally occurring hormone your body releases after eating. The compounded version is prepared by licensed pharmacies and contains the same active ingredient as the brand-name medications Ozempic (approved for type 2 diabetes) and Wegovy (approved for chronic weight management).
How it works
Semaglutide acts on receptors in the brain and gut. It signals satiety, slows gastric emptying, and dampens food cravings. Most members notice meaningful appetite suppression within the first 1 to 2 weeks. Doses are titrated upward over time to balance effectiveness with side-effect tolerance.
Who it's for
Adults with a BMI of 27 or higher, or 25 with weight-related conditions, who want a medically supervised path to sustained weight loss. Not for everyone — your provider screens for contraindications including personal or family history of medullary thyroid carcinoma, pancreatitis, or active gallbladder disease.
Benefits
- 15 to 20% average body-weight reduction over 12 to 18 months when paired with lifestyle support
- Same active ingredient as Ozempic and Wegovy
- Flexible compounded dosing for tolerance and titration
- Strong safety profile in long-term clinical use
- Free shipping nationwide
Things to consider
- Mild nausea and reduced appetite are most common in the first weeks
- Compounded medications are not FDA-approved as finished products
- Insurance typically does not cover compounded GLP-1 medications
- Requires consistent self-injection (weekly)
Get started
See if Semaglutide is right for you
Starts at $197 the first month.
Semaglutide FAQ
Is compounded semaglutide the same as Ozempic?
How long does it take to work?
Can I take semaglutide long-term?
Related
Compounded medications are not FDA-approved. All prescriptions require evaluation and approval by an independently licensed medical provider. Individual results vary.